Characteristics, Treatment, Outcomes, and Cause of Death of Invasively Ventilated Patients with COVID-19 ARDS in Asir Central Hospital, Southern of Saudi Arabia: A Retrospective Single Center Experience

Ali Al Bshabshe

King Khalid University Abha, Saudi Arabia.

Mushary S. Alqahtani *

AFHSR, Khamis Mushait, Saudi Arabia.

Khaled A. Amer

ACH, Abha, Saudi Arabia.

Najla A. Jahash

ACH, Abha, Saudi Arabia.

Abdullah Al Thawwab

KAMC, Makkah, Saudia Arabia.

Osama A. Saleh

King Khalid University, Abha, Saudi Arabia.

Ahmed A. Alasim

AFHSR, Khamis Mushait, Saudi Arabia.

*Author to whom correspondence should be addressed.


Abstract

Introduction: COVID-19's emergence caused devastating consequences worldwide, with high morbidity and mortality rates. Critically ill patients face challenges like acute respiratory failure requiring intensive measures, including mechanical ventilation. Mortality rates in ARDS are influenced by various factors. This paper focuses on describing characteristics, management, and survival factors of mechanically ventilated ICU patients in Saudi Arabia.

Methods: A retrospective, noninterventional approach, we reviewed charts and data of all COVID-19-infected patients who were admitted to the ICU, particularly those requiring ventilation support at Aseer Central Hospital (ACH) in the southern region of Saudi Arabia.

Results: The study enrolled 594 COVID patients, mean age 60.5 ± 17.3 years, with 67% males. Approximately half had O negative blood group. Common chronic health issues: diabetes mellitus (35.5%). Positive culture findings in almost 340 (57.2%), with Klebsiella pneumoniae being the most isolated microorganism (45.5%). Significant correlations found with mortality: age, blood culture, Rh positive group (P<0.05).

Conclusion: This study provides critical insights into the clinical and epidemiological aspects of COVID-19 patients admitted to the ICU in a Saudi Arabian hospital. The research underscores the impact of age, comorbidities, laboratory markers, and treatment interventions on patient outcomes, emphasizing the significance of tailored management strategies in this context.

Keywords: COVID-19, patient, blood culture, mortality, myalgia


How to Cite

Bshabshe, A. A., Alqahtani, M. S., Amer, K. A., Jahash, N. A., Thawwab, A. A., Saleh, O. A. and Alasim, A. A. (2024) “Characteristics, Treatment, Outcomes, and Cause of Death of Invasively Ventilated Patients with COVID-19 ARDS in Asir Central Hospital, Southern of Saudi Arabia: A Retrospective Single Center Experience”, Journal of Pharmaceutical Research International, 36(8), pp. 104–113. doi: 10.9734/jpri/2024/v36i87562.