Systemic Sclerosis: A Case Report and Review of Current Advances in Treatment
Aishwarya Shankar *
Chettinad Hospital and Research Institute, Chettinad Health City, Rajiv Gandhi Salai (OMR), Kelambakkam, Tamil Nadu-603103, India.
Jayakar Thomas
Chettinad Hospital and Research Institute, Chettinad Health City, Rajiv Gandhi Salai (OMR), Kelambakkam, Tamil Nadu-603103, India.
*Author to whom correspondence should be addressed.
Abstract
Systemic sclerosis (SSc) is a chronic multisystem disease characterized by excess deposition of connective tissue in skin and internal organs, associated with microvasculature changes and immunologic abnormalities.
We hereby report a case of scleroderma in a 52 year old female with classical clinical and histopathological findings. The latter part of this article discusses and reviews existing and novel emerging therapies for the treatment of SSc, with an emphasis on recent trials targeting the cutaneous and pulmonary manifestations of this disease.
Keywords: Scleroderma, systemic sclerosis, chronic multisystem disease, immunologic abnormalities