Preliminary Phytochemical Analysis and Assessment of Antioxidant and Anti Cholesterol Activity of Ethanolic Leaf Extract of Acalypha indica linn
E. Ilammaran Varshan
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-600 077, India.
S. Kavitha
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-600 077, India.
R. Gayathri *
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-600 077, India.
V. Vishnupriya
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-600 077, India.
J. Selvaraj
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-600 077, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Acalypha indica Linn. is a weed plant found in shady wetlands. It is commonly called as kuppai meni in Tamil, belonging to the family Euphorbiaceae. It is found to be one of the greatest Indian plants with anti-venom, antibacterial, antiviral and antimicrobial properties.
Aim:Preliminary phytochemical analysis and assessment of antioxidant and anti cholesterol activity of ethanolic leaf extract of acalypha indica linn
Materials and Methods: Phytochemical screening and in vitro antioxidant and hypolipidemic potential of Acalypha indica Linn.was analysed as per the standard methods. The data were analyzed statistically by one-way analysis of variance (ANOVA) followed by Duncan’s multiple range test and it was used to see the statistical significance among the groups. The results with the p<0.05 level were considered to be statistically significant.
Results: Ethanolic leaf extract of Acalypha indica Linn exhibited a significant antioxidant and hypolipidemic activity and increased in a dose dependent manner as compared to the standard drug.
Conclusion: Many researchers are working towards replacing synthetic drugs with herbal alternatives. Herbal extracts are natural and will aid in longevity.
Keywords: Acalypha indica, weed plant, standard drugs, In-vitro analysis of antioxidant and anti cholesterol, innovative technology, novel method