Theranostics Nanomedicine: Recent Advancement, Applications and Challenges
Shailesh Ghaywat
Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.
Payal Dhande
Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.
Sneha Gaurkar
Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.
Samiksha Upadhyay
Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.
Vaishnavi Raut
Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.
Neha Binjhade
Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.
Kamlesh Wadher *
Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.
Milind Umekar
Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
Many advancements have been made in treatment and diagnosis tools with the progress in modern medicine and technology. Theronostics are multifunctional nanomaterials that combine therapeutic as well as imaging functions. Theranostic nanomedicines are used for checking drug release and efficacy. The amalgamation of diagnostic and therapeutic agents within a single system provides the target site localization and accumulation of nanomedicines in organs.It provides a transition from conventional medicine to personalized medicine. Many different types of nanomedicines have been evaluated over the years. Theragnostics approach includes pharmacogenomics, personalized medicine and imaging to develop efficient new targeted therapies which will help in better and optimize drug selection along with monitoring the therapy response to increase drug safety and efficacy. This review summarizes the recent development and various nanocarriers developed for nanotheranostics, includes inorganic Nanoparticles, Polymeric, dendrimers, micelles, liposomes, metallic, and carbon nanotubes.
Keywords: Theranostics, nanomedicine, nanoparticles, personalized therapy, liposomes, targeting