A Review on Emerging Therapeutic Interventions for Corona Virus
Muhammad Yasir Waqas
Department of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences Bahawalpur 63100, Pakistan.
Muhammad Arshad Javid
Department of Biosciences, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Muhammad Mudasser Nazir
Department of Pathobiology, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Azhar Aslam
Department of Microbiology, Faculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Sheraz Ahmed Bhatti
Department of Pathobiology, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Asim Faraz
Department of Livestock and Poultry Production, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Qaiser Akram
Department of Pathobiology, KBCMA, College of Veterinary and Animal Sciences, Narowal Campus, University of Veterinary and Animal Sciences, Lahore 51801, Pakistan.
Nasir Niaz
Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, Multan 60800, Pakistan.
Muhammad Farrukh Nisar
Department of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences Bahawalpur 63100, Pakistan.
Tanveer Ahmed
Department of Clinical Sciences, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Muhammad Asif
Institute of Continuing Education, University of Veterinary and Animal Sciences, Lahore 54600, Pakistan.
Muhammad Haseeb Khaliq
Department of Anatomy and Histology, Cholistan University of Veterinary & Animal Sciences, Bahawalpur 63100, Pakistan.
Shaukat Munawar
Department of Pharmacology & Toxicology, Cholistan University of Veterinary & Animal Sciences, Bahawalpur 63100, Pakistan.
Zahid Manzoor
Department of Pharmacology & Toxicology, Cholistan University of Veterinary & Animal Sciences, Bahawalpur 63100, Pakistan.
Qurban Ali *
Institute of Molecular Biology and Biotechnology, University of Lahore, Lahore, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
The Coronavirus (SARS-CoV-2) is one of the deadliest viruses of current era and is identified as the causative agent of novel coronavirus disease-2019 (COVID-19). This disease stances a severe risk to mankind due to its unexplored pathologies. It was declared as a COVID-19 pandemic by the world health organization. This outbreak has challenged the public health concerns at large, killing the most vulnerable person, causing generalized panic and become a top debate among scientists, clinicians, physicians, pathologists, economists, athletes and politicians. Anti-viral vaccines and target drugs to treat this virus are unavailable due to its diverse genetic instability. Currently, its prevention, control and treatment are questionable as no proven remedies have been effective for its cure so far. From a research assessment, many number of drugs or medicines are being manufactured and tested at fast pace, goals and objectives are being celebrated on daily basis, and also many drugs are be subjected to clinical tests. Scientists are interested about how to provide the better care to everyone before a vaccine can be made available to common community. To stop COVID-19, effective solutions (i.e., personal protection elements, vaccines, drugs, etc.) are needed urgently. Red bells are ringing but there is no way out. Current review focuses on the ongoing regimes and therapeutic interventions for better combat with COVID-19.
Keywords: Coronavirus, genetic instability, interventions, pandemic, therapeutic, vaccine