Review on Targeted Drug Delivery in Pancreatic Cancer
Chinnarao Pinisetti
University Institute of Pharma Sciences, Chandigarh University, Mohali, Punjab-140413, India.
Vimal Arora *
University Institute of Pharma Sciences, Chandigarh University, Mohali, Punjab-140413, India.
*Author to whom correspondence should be addressed.
Abstract
Targeted delivery systems are the advanced systems where the active pharmaceutical ingredient is delivered accurately to the specific site for the necessary pharmacological action and better therapeutic Index. The main motto of these transport systems is to increase the drug activity at specific target sites with a low amount of drug as compared to high doses of conventional dosage forms. This helps to reduce the side effects of medication, as the drug acts directly at the specific tissues or cells and shows its intended action at the given concentration without getting dissipated in the other areas of the body or the surrounding environment. The evolution of these new approaches plays a vital role in the treatment of chronic diseases like diabetes, tumors, and cancer, etc. This context mainly talks about the delivery agents for the treatment of pancreatic cancer, delivery agents, and the recent advancements made in this area.
Keywords: Target delivery systems, liposomes, nanoparticles, carbon nanotubes, dendrimers, layered double hydroxides, micelles, SMART DDS