Overview on Disorders of Oral Pigmentation

Rakan Saifuddin Shaheen

Department of Preventive Dentistry, Riyadh Elm University, Riyadh, Saudi Arabia.

Abdulrahman Kamal Habash

MOH, Riyadh, Saudi Arabia.

Firas Walid Basoudan

MOH, Riyadh, Saudi Arabia.

Hassan Adnan Alwayel

MOH, Riyadh, Saudi Arabia.

Bassam Walid Alarfaj

Riyadh Elm University, Riyadh, Saudi Arabia.

Ali Naji Alwayel

Riyadh Elm University, Riyadh, Saudi Arabia.

Jafar Ali Alaithan

Riyadh Elm University, Riyadh, Saudi Arabia.

Abdullah Hamoud Al Gharbi

Dammam College of Technology, Saudi Arabia.

Abdulrahman Aldayel

King Abdullah Bin Abdulaziz University Hospital (KAAUH), Saudi Arabia.

Mohammed Jawad albaqshi

Anees Clinic , Easter Province, ElHasa , Saudi Arabia.

*Author to whom correspondence should be addressed.


Abstract

Oral pigmentation is a very frequent disorder that can affect any area of the mouth. Oral pigmentation can be a symptom of a physiologic or pathologic condition. There are a variety of reasons, ranging from basic iatrogenic processes like dental amalgam implantation to sophisticated medical illnesses like Peutz-Jeghers syndrome (PJS) and Addison disease. pathologic pigmentation can be classed as exogenous or endogenous. Drugs, tobacco/smoking, amalgam tattoos, or heavy metals can all cause exogenous pigmentation. Endogenous pigmentation is linked to endocrine abnormalities, syndromes, infections, chronic irritation, and reactive or neoplastic conditions. For any oral pigmented lesion that is not easily identified, clinicians must physically evaluate the oral cavity, gather clinical histories, and be willing to do a biopsy. Management depends on the causing factor of the oral pigmentation disorder and thus multiple approaches can be considered. The decisive therapy for early-stage melanoma is surgery, such as broad local excision with sentinel lymph node biopsies, elective node dissection, or both.

Keywords: Oral pigmentation, oral health, pigmentation alterations, oral disorders, smoking


How to Cite

Shaheen, Rakan Saifuddin, Abdulrahman Kamal Habash, Firas Walid Basoudan, Hassan Adnan Alwayel, Bassam Walid Alarfaj, Ali Naji Alwayel, Jafar Ali Alaithan, Abdullah Hamoud Al Gharbi, Abdulrahman Aldayel, and Mohammed Jawad albaqshi. 2021. “Overview on Disorders of Oral Pigmentation”. Journal of Pharmaceutical Research International 33 (60B):1093-99. https://doi.org/10.9734/jpri/2021/v33i60B34718.

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