Erythema Dyschromicum Perstans: The Spotty Possibility – A Rare Case Report
M. Naga Meena Lochini
Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, India.
F. K. Jasima Nilofer *
Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, India.
S. Mary Lilly
Department of Pathology, Sree Balaji Medical College and Hospital, Chennai, India.
*Author to whom correspondence should be addressed.
Abstract
Erythema Dyschromicum Perstans (EDP) / Ashy Dermatosis are a less common dermatological disorder with an unknown etiology. It is characterized by asymptomatic, grey, symmetric and confluent macules all over the body. Herein, we report a case of a 50 years old man who presented clinically, with diffuse, patchy pigmentation having ill-defined, erythematous borders involving bilateral arms and forearms. Histopathological examination of the lesion biopsy demonstrates vacuolar degeneration of the basal cell layer, dermal perivascular mononuclear cell infiltrate and increased epidermal melanin pigment and presence of dermal melanophages. For the present case, treatment with Clofazimine has proven to be effective.
Keywords: Erythema dyschromicum perstans, ashy dermatosis, dermal melanophages, clofazimine