Exploring the Relationship between Bowel Microbiota and Impaired Glucose Tolerance
Attia Ahmed Attia
Department of Botany and Microbiology, Faculty of Science, Benha University, Benha, Egypt.
Alaa Elmetwalli
Department of Clinical Trial Research Unit, Egyptian Liver Research Institute and Hospital, Mansoura, Egypt.
Jayda G. Eldiasty
Biology Department, University College of Haqel, University of Tabuk, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Background and Aim: Because of the large number of genes found in the gut microbiome, it has recently been determined that numerous human microorganisms have significant implications for human health.
Aim: The significance of gut bacteria in the development of T2DM was investigated in this study.
Materials and Methods: Microbial species were extracted from fecal materials; they were identified and quantified using genomic spectrophotometric equipment, and certain biochemical parameters for Diabetes were quantified.
Result: We observed a concentration of firmicutes, Bacteroides, and proteobacteria, with the Escherichia coli population predominating. Biochemical parameters reveal a several-fold raised value for some biomarkers in T2DM. In a paired sample test results gave significant differences for all tested pairs.
Conclusion: Microbiomes can affect the gut environment and trigger alterations that embolden the development of T2DM, according to study findings.
Keywords: Microbiota, type 2 DM, impaired glucose tolerance