Journal of Pharmaceutical Research International

Introduction: Thrombocytopenia is an autoimmune condition in which there is an abnormal low level of platelets. This is also called as Thrombopenia. The word Thrombocytopenia is derived from English word “Thrombocyte” which means “Platelet” and Greek word “Penia” which means “Poverty’.

Clinical Findings: Persistent reddish lesion, generalized weakness.

Diagnostic Evaluation : Blood test – Hb-11.2 %,RBC -6.06 million /cu mm , Total WBC Count – 10400 /cu mm , Platelet -0.25 lacs /cu mm , Monocyte – 0.6, Granulocyte – 44 % Lymphocyte -48 % , RDW -15.2 % , HCT-35.8%,Prothrombin Time -1.02 (12.8), APTT (Patient Count ) 30.7 % , RBS -104 mg/dl.

Peripheral Smear: RBCs-Predominantly normocytic mildly hypochromic with few microcytic RBCs seen. Platelets –Reduced on smear. APC -37000 cells / mm cu as per cell counter no haemoparasit seen. Antinuclear Antibodies (ANA) by  Enzyme - linked Immunoassay Lactate Dehydrogenase. Method -0.69 LDH – 205 Ultrasonography – Grade 1 fatty liver.

Therapeutic Intervention: 5 unit platelet concentrate transfusion, Inj. Methyl Prednisolone 500 mg × (2 Days), Tab. Prednisolone 30 mg  Tab. Autrin  , Tab. Metformin 1 gm  , Tab. Glipizide 5 mg.

Outcome: After treatment, patient show improvement. His platelet count was improved and sugar level were normal and his platelet count increased from 0.45 lacs /cu mm to 0.25 lacs / cu mm after platelet transfusion.

Conclusion: My patient was admitted in High Dependency Unit. Archya Vinobha Bhave Rural Hospital with a case of Thrombocytopenia and he had complaint of persistent reddish lesion, generalized weakness. After getting appropriate treatment, his condition was improved.