Journal of Pharmaceutical Research International

Objective: To determine the frequency of bile duct injury during laparascopic cholecystectomy procedures.

Study Design: This is an observational study.

Setting: Study carried out at General Surgery department, Shaheed Benazir Bhutto Medical College, Lyari Karachi, from July 2019 to August 2021.

Materials and Methods: All diagnosed patients of gallstones on the clinically and findings of ultrasound of abdomen with age (20-60 years), gender were included in study. Patient not willing for surgery, pregnant ladies, bleeding disorders, obstructive jaundice and carcinoma of gall bladder were excluded from this study.

Results: Out of 162 patients, there were 15 males (9.25%) and 147 females (90.74%), with a male to female ratio of 1:11.6. The mean age was 36.01±8.11years (20 to 60 years). According to our observation, there were 6 cases (3.70%) of common bile duct injury during the operation. Treatments offered range from ERCP and conservative treatment to reconstructive surgery. Four patients (2.46%) were converted to open cholecystectomy, 1 patient underwent open cholecystectomy subsequent ERCP, and 1 patient underwent open Cholecystectomy with Subsequent Reconstructive surgery.

Conclusion: In our study bile duct injury commonly occur during laparoscopic cholecystectomy. Over time, improving surgical technique and experience reduced the overall incidence of CBD injuries.