Abies webbiana Mediated Zinc Oxide Nanoparticles and Its Anti-inflammatory Activity
S. Priyadharshini
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
M. Jeevitha *
Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
S. Rajeshkumar
Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Selvaraj Jayaraman
Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Green nanoparticle synthesis provides a number of advantages, including being environmentally friendly, taking less time, being less expensive, being more stable, and, most significantly, not requiring the use of harmful chemicals.
Aim: The aim of the present study is to evaluate the anti-inflammatory activity of zinc oxide [ZnO] nanoparticles prepared using Abies webbiana extract.
Materials and Methods: In this study, ZnO nanoparticles were characterised using ultraviolet-visible spectroscopy and inhibition of albumin denaturation assay using A. webbiana extract.
Results: The biosynthesised ZnO particles exhibited potent anti-inflammatory activity to inhibit COX activity. ZnO nanoparticles can be developed as a novel medicine and can be used as an alternative to commercially available anti-inflammatory agents, thus reducing the major health problems.
Conclusion: Using A.webbiana extract, the findings suggest a cost-effective and environmentally friendly production of ZnO nanoparticles. ZnO nanoparticles mediated by A. webbiana showed promising properties. More investigations are required to understand the properties of these nanoparticles, which have a wide range of medical and dental applications.
Keywords: Abies webbiana, anti-inflammatory, innovative technology, zinc oxide nanoparticles