Anticancer Activity of "Ziziphus jujuba" - A Review
U. Vidhya Rekha *
Department of Public Health Dentistry, Sree Balaji Dental College and Hospital, Chennai, India.
S. Bhuminathan
Department of Prosthodontics, Sree Balaji Dental College and Hospital, Chennai, India.
P. Ravi Shankar
Department of Public Health Dentistry, Rajas Dental College and Hospital, Kavalkinaru, Tirunelveli Dist., India.
*Author to whom correspondence should be addressed.
Abstract
Ziziphus jujuba Mill. (Z. jujube) is a conventional plant that has a long history of usage in nutrients and the therapeutic interventions of a wide range of ailments. It grows mainly in South and East Asia, and also in Australia and Europe. Mounting data supports the health advantages of Z. jujuba, including anticancer, anti-inflammation, anti-obesity, antioxidant, and hepato- and gastrointestinal protective characteristics. Chemotherapy, particularly with cis-diamminedichloroplatinium (CDDP, cisplatin) and its derivatives, is commonly used to treat cancer. Although it is an effective therapy for human tumors, drug resistance impedes successful treatment. A better knowledge of the processes and develop strategies to address chemoresistance can improve patient outcomes dramatically. Numerous researchers have recently focused their attention on the increasing occurrence of numerous types of malignancies worldwide. The anticancer efficacy of Z. jujuba was discussed in this review study.
Keywords: Medicinal plant, anticancer activity, Ziziphus jujuba