Management of Chemotherapy Induced Mucositis
Ashwag Siddik Noorsaeed *
Consultant Restorative Dentist, Saudi Arabia.
Mawaddah Saad Aljohani
King Abdulaziz University, Saudi Arabia.
Khawlah Salem A. BinAfif
King Abdulaziz University, Saudi Arabia.
Rafal Abdulrahman Alsaywed
King Abdulaziz University, Saudi Arabia.
Maha Ali Bakhshwain
King Abdulaziz University, Saudi Arabia.
Reham Mohammed Alharbi
King Abdulaziz University, Saudi Arabia.
Heba Abdulhakeem M. Bukhari
King Abdulaziz University, Saudi Arabia.
Omar Mohammed Albalushi
King Abdulaziz University, Saudi Arabia.
Ahmad Abdulrahman Aljuhani
King Abdulaziz University, Saudi Arabia.
Amal Abdullah Batarfi
King Abdulaziz University, Saudi Arabia.
Awatif Fakhri Subahi
King Abdulaziz University, Saudi Arabia.
Azzah Mohammed S Alghamdi
King Abdulaziz University, Saudi Arabia.
Moyssar tariq khallaf
King Salman Armed Forces Hospital, Saudi Arabia.
Zainah Ali Asiri
King Khalid University, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Oral mucositis is a severe ailment that causes erythema, edema, and ulceration of the oral mucosa, as well as pain and oral intake restrictions. Chemotherapy and radiation therapy are the most often utilized cancer treatment options. Despite the fact that these treatments are used to improve a patient's quality of life, they are linked to a number of negative side effects. Oral mucositis is a common side effect in patients undergoing head and neck radiation therapy. While some chemotherapy-related side effects are being better managed, mucositis is becoming more common. Reducing patient risk factors, adopt proven preventative measures, and optimize supportive care practices targeted to the patients' needs and symptoms are all recommendations that can be made. In clinical practice and research, a variety of measures have been used to record the amount and severity of oral mucositis. The World Health Organization (WHO) scale is a simple, easy-to-use scale that can be used in clinical practice on a regular basis. There are multiple approaches for management of Mucositis. Cryotherapy, palifermin, and sucralfate are among the three therapies that showed statistically significant effect in avoiding or lowering the severity of mucositis according to reports. In this article we’ll be looking at Chemotherapy induced mucositis, its etiology, epidemiology, evaluation. And most importantly management.
Keywords: Oral mucositis, erythema, oral mucosa, edema, epidemiology, chemotherapy