Overview on Gastrointestinal Stromal Tumor; A Review
Hashem Bark Awadh Abood *
General Surgery, Dr Samir Abbas Hospital , Jeddah King Fahad hospital – Albaha, Saudi Arabia.
Amani Nasser D. Albalawi
Royal Collage of Surgeons in Ireland (University of Medicine and Health Science), KSU.
Haifa Obedullah AlEnazi
Buraidah Central Hospital, Saudi Arabia.
Mousa Mutlaq Almuhanna
Qassim University, Saudi Arabia.
Norah Othman Busaad
King Faisal University, Saudi Arabia.
Rafa Ghazi Ali Jarad
Prince Mohammed Bin Nasser Hospital, Saudi Arabia.
Mahdi Saleh Alkhamis
King Faisal General Hospital, Saudi Arabia.
Shahad Majed Alsharif
Taif University, Saudi Arabia.
Mutaz Abdulrahman S. Alahdal
King Abdulaziz University, Saudi Arabia.
Deena Ahmed S. Alqahtani
Dammam Central Hospital, Saudi Arabia.
Abdulmajeed Ramzy Alhakamy
Huraymala General Hospital, Saudi Arabia.
Sulaiman Abdullah Alraqibah
Qassim University, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
GISTs (gastrointestinal stromal tumours) are benign tumours that most usually affect the gastrointestinal (GI) system. GISTs can strike at any age, however they are most typically diagnosed in later life, with a median diagnostic age in the 60s. Abdominal ultrasound, CT scan, magnetic resonance imaging (MRI), and positron emission transverse tomography (PET) can all be used to detect GISTs (PET).CT enterography is the most effective method for determining the location of these tumors. Histopathology and immunochemistry are used to diagnose GISTs. Surgical excision remains the therapy of choice for gastrointestinal stromal tumours more than 2 cm that are readily resectable. Due to the possibility of resistance to standard treatment, mutational analysis should be undertaken when considering adjuvant and neoadjuvant therapy. In this review we’ll be looking at the disease etiology, epidemiology, diagnosis and management.
Keywords: Gastrointestinal stromal tumours, tumor, GIT, surgery