Medicinal Plants Explain the Significant Role of Uric Acid for Malaria Parasite
Mosab Nouraldein Mohammed Hamad *
Department of Microbiology, Faculty of Medicine, Nile Valley University, Atbara, Sudan.
Sufian Khalid M. Noor
Department of Medicine, Faculty of Medicine, Nile Valley University, Atbara, Sudan.
Awadalla H Kashif
Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan.
Mohammed Medani Eltayeb
Faculty of Medical Laboratory Sciences, Alneelain University, Khartoum, Sudan.
Abdelgadir Elamin Eltom
Medical Laboratories Department, College of Health Sciences, Gulf Medical University, Ajman, UAE.
Praveen Kumar Kandakurti
College of Health Sciences, Gulf Medical University, Ajman, United Arab Emirates.
Elizabeth Popova
College of Health and Allied Sciences, St. Joseph University In Tanzania , Dar Es Salaam, United Republic of Tanzania.
Shafie Abdulkadir Hassan
Department of Medical Laboratory Sciences, Jamhuriya University of Science and Technology , Mogadishu , Somalia.
Yassin Bakri Salih
Reference Diagnostic laboratory , Ministry of Health and Population, Atbara, River Nile State , Sudan.
Tarig Mohammed Elfaki
Academy of Health Science, Federal Ministry of Health, Khartoum , Sudan.
Mohammed Ahmed Ibrahim Ahmed
Department of Microbiology, Faculty of Medicine, Nile Valley University, Atbara, Sudan.
*Author to whom correspondence should be addressed.
Abstract
Medicinal plants, recognized and employed in conventional medicine practices since prehistoric era. Plants produce thousands of chemical substances for functions counting defence against insects, fungi, bacterial and parasitic diseases.
Malaria is most widespread parasitic infection , it caused by coccidian protozoa of the genus plasmodium , four species are mostly infect human, P. falciparum, P. vivax, P. malriae and P. ovale, Majority of malaria cases resulted from P. falciparum and P. vivax.
Uric acid regarded as one of the damaging molecular patterns of malaria parasite infection, and in this review we discussed the potential role of medicinal plants used as antimalarial to diminish the level of uric acid in gout patients. These may suggest that most of the complication associated with malaria, may attributed to amplified level of uric acid . Experimental studies recommended.
Keywords: Uric acid, malaria parasite, medicinal plants, malaria, hyperuricemia