Bio-analytical Approach for Stability Studies of Bendroflumethiazide Materials
B. Veeraswami *
Department of chemistry, GITAM Institute of Science, GITAM Deemed to be University, Visakhapatnam, PIN-530045, India.
V. M. K. Naveen
Department of chemistry, GITAM Institute of Science, GITAM Deemed to be University, Visakhapatnam, PIN-530045, India.
*Author to whom correspondence should be addressed.
Abstract
In this paper a comprehensive study of stability related, and evidence based best practices of Bio-analytical stability on Bendroflumethiazide drug samples are studied. The proposed approach is very significant and essential for the drugs development process address the specify the acceptancy, purity, efficacy, prediction of strength and quality of the drugs. The stability study constituents several methods like Bench-Top, Auto-sampler, Freeze-Thaw, Dry-extract, Wet-extract, Short-term, long-Term stability studies at relative intervals results the complete stability information about the drug under the proposed and validated method. There ported out comes of this methos shows this drug have good stability according to ICH guidelines.
Keywords: Bio-analytical, bendroflumethiazide, auto-sampler, short term, wet-extract, ICH guidelines