Comparative Evaluation of Open Flap Debridement Therapy with Two Different Types of Platelet Concentrates, T-PRF and L-PRF as Adjuncts- A Systematic Review

Gowri Pendyala *

Department of Periodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra, India.

Ekta Srivastava

Department of Pedodontics, S.M.B.T Dental college and Hospital, Sangamner, Dist. Ahmednagar, Maharashtra, India.

Babita Pawar

Department of Periodontics, Chhattisgarh dental college and research institute, Rajnandgoan, Chhattisgarh, India.

Satish Manthena

Department of Periodontics, Drs Sudha and Nageshwar Rao Siddhartha Instotute of Dental Sciences, Vijayawada, Andhra Pradesh, India.

Swati Pustake

Department of Prosthodontics and Crown and Bridge, MGV KBH Dental College and Hospital, Nashik, Maharashtra, India.

Saurabh Joshi

Department of Periodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra, India.

Ameet Mani

Department of Periodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra, India.

Vidyasagar Mopagar

Department of Periodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, Ahmednagar, Maharashtra, India.

*Author to whom correspondence should be addressed.


Abstract

Conventional Periodontal therapy such as scaling and root planing and open flap debridement aims to halt the inflammation process and promotes repair of disease-related defects. Current regenerative procedures offers a limited potential toward attaining a complete periodontal restoration and none is considered a gold standard in the treatment of intrabony defects. This study was done to compare the efficiency of Titanium-Platelet Rich Fibrin and Leukocyte-Platelet Rich Fibrin as adjuncts to Open Flap Debridement  therapy to treat intra-bony periodontal defects. A search was conducted through PubMed and various other databases such as Cochrane, Google Scholar and EBSCO Host , under the key words, OFD , T-PRF,L-PRF, Clinical Outcomes, Comparison and  Randomised Contolled Trials. Six relevant articles were selected for analysis. Compared to non-platelet concentrates, L-PRFproves to be the better adjunct to open flap debridement therapy. When compared to T-PRF, however, L-PRF has comparatively inferior properties of bone defect resolution and fill.We can conclude that T-PRF has better properties, greater bone defect fill and defect resolution as compared to L-PRF.

Keywords: Regeneration, open flap debridement, titanium-PRF, leukocyte-PRF, intrabony defect


How to Cite

Pendyala, G., Srivastava, E., Pawar, B., Manthena, S., Pustake, S., Joshi, S., Mani, A. and Mopagar, V. (2021) “Comparative Evaluation of Open Flap Debridement Therapy with Two Different Types of Platelet Concentrates, T-PRF and L-PRF as Adjuncts- A Systematic Review”, Journal of Pharmaceutical Research International, 33(54B), pp. 263–271. doi: 10.9734/jpri/2021/v33i54B33785.