A Review on Cardioprotective Mechanism of Chemical Constituents of Medicinal Plants
Sreya Kosanam *
Department of Pharmacology, KL College of Pharmacy, Koneru Lakshmaiah Education Foundation Deemed to be University, Green Fields, Vaddeswaram, Andhra Pradesh, India.
Rajeshwari Pasupula
Department of Pharmacology, KL College of Pharmacy, Koneru Lakshmaiah Education Foundation Deemed to be University, Green Fields, Vaddeswaram, Andhra Pradesh, India.
*Author to whom correspondence should be addressed.
Abstract
Plants are the major source of human living. Since the beginning of the era, plants have been used for medicinal purposes. There is dire to explore the mechanism of chemical constituents in plants and particularly saponins, cardiac glycosides, and flavonoids due to their mechanism to save damaged cells in cardiac muscle. Databases like Google Scholar, Medline, PubMed, and the Directory of Open Access Journals were searched to find the articles describing the cardioprotective mechanism of medicinal plants. Saponin, flavonoids, glycoside, steroid, alkaloids, tannin, phenol, phlorotannin, terpenoids, and anthraquinone are chemical constituents in plants that enhance cardioprotection activity and decreases cardiac abnormalities. The current review article provides data on the use of medicinal plants, specifically against cardiac diseases, as well as an investigation of molecules/phytoconstituents as plant secondary metabolites for their cardioprotective potential.
Keywords: Cardioprotective, medicinal plants, oxidative stress, saponins, cardiac glycosides