Emerging Echinocandin Resistance – A Review
P. Sneka *
Department of Microbiology, Bhaarath Medical College and Hospital, Selaiyur, Tambaram, Chennai, India.
Mahalakshmi Krishnan
Department of Microbiology, Sree Balaji Dental College and Hospital, Chennai, India.
V. Sangamithra
Department of Microbiology, Bhaarath Medical College and Hospital, Selaiyur, Tambaram, Chennai, India.
*Author to whom correspondence should be addressed.
Abstract
Worldwide there is a steady increase in the number of fungal infections each year. Simultaneously, there is a high rise of antifungal resistance among the Candida isolates. This has now become a major concern in hospitalized patients resulting in poor treatment outcome. Echinocandins, a new group of antifungals has given promising results inspite of its increasing rate of resistance exhibited by some Candida species.
Keywords: Antifungal resistance, echinocandins, candida species, fungal infections, antifungal drugs, antifungal therapy, fungicidal activity