Niosomes: A Promising Drug Delivery System in Transdermal Drug Delivery (TDDS)

Vibhavari M. Chatur

Department of Pharmaceutics, PES Modern College of Pharmacy, Moshi, Pune 412105 Maharashtra India.

Shashikant N. Dhole *

Department of Pharmaceutics, PES Modern College of Pharmacy, Moshi, Pune 412105 Maharashtra India.

*Author to whom correspondence should be addressed.


Abstract

Infectious disease treatment and immunisation have undergone a transformative change in recent years. With the advancement of biotechnology and genetic engineering, a large number of disease-specific biological have been created, as well as a focus on delivering these biological effectively. Niosomes are vesicular Nano carriers that are gaining popularity as a potential transdermal drug delivery system due to properties like enhanced drug penetration, a local depot for sustained drug release, and a rate-limiting membrane for modulating systemic absorption of drugs through the skin. Niosomes are non-ionic surfactant-based vesicles that are biodegradable, relatively nontoxic, more stable, and less expensive than liposomes. This analysis gives a high-level overview of niosomes, including their chemical composition, structure, benefits, and applications, as well as some general observations on niosomes as percutaneous permeation enhancers.

Keywords: Niosomes, drug delivery system, transdermal drug delivery


How to Cite

Chatur, V. M. and Dhole, S. N. (2021) “Niosomes: A Promising Drug Delivery System in Transdermal Drug Delivery (TDDS)”, Journal of Pharmaceutical Research International, 33(48B), pp. 6–17. doi: 10.9734/jpri/2021/v33i48B33254.