A Case of Budd-Chiari Syndrome – As an Unusual Early Manifestation of Systemic Lupus Erythematosis with Antiphospholipid Syndrome and Deep Vein Thrombosis
Gitanjali Dasari *
Department of General Medicine, Chettinad Hospital and Research Institute, Kelambakkam, India.
S. Selvamani
Department of General Medicine, Chettinad Hospital and Research Institute, Kelambakkam, India.
E. Dhivya
Department of General Medicine, Chettinad Hospital and Research Institute, Kelambakkam, India.
V. R. Mohan Rao
Department of General Medicine, Chettinad Hospital and Research Institute, Kelambakkam, India.
*Author to whom correspondence should be addressed.
Abstract
Budd-Chiari syndrome occurs due to obstruction of hepatic venous out-flow which in turn produces intense congestion of the liver. Systemic Lupus Erythematosus (SLE), which is an auto-immune disorder has protean manifestations such as easy fatiguability, arthralgia, photosensitivity, malar rash, fever, alopecia but our case had an unique association of ascites and hepatosplenomegaly due to Budd Chiari syndrome stemming from the root cause of Antiphospholipid antibody syndrome (APLA) is very rare. SLE accounts for 40% of the cases of APLA. SLE presenting with Budd-Chiari syndrome as an early manifestation is unusual and is rarely reported in the literature. Here we report a rare case of a young female who presented with abdominal distension, abdominal pain and fever diagnosed to have Budd-Chiari syndrome as a presenting feature of SLE and on further evaluation she was also found to have antiphospholipid syndrome secondary to SLE.
Keywords: Antiphospholipid syndrome, SLE, Budd-Chiari syndrome