Study on Antibiotic Prescribing Pattern in the In-Patient Surgery Department of Tertiary Care Teaching Hospital Using WHO Indicator
Mamta Naagar *
Department of Pharmacy Practice, M.M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana -Ambala (Haryana)– 133207, India.
Aishwarya Gangwar
Department of Pharmacy, M.M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana -Ambala (Haryana)– 133207, India.
Akhilesh Patel
Department of Pharmacy Practice, DDR College of Pharmacy, B D Sharma University, Rohtak, Haryana– 124001, India.
*Author to whom correspondence should be addressed.
Abstract
Aims: The evaluation of antibiotic agents conveyed is critical for guaranteeing that the quality and fittingness of therapy. The study's purpose was to assess the use of antibiotics on the basis of WHO indicator in surgery department.
Study Design: A prospective observational study was carried out in the surgery inpatient department for a period of six months after the approval of the ethical committee in tertiary care hospital.
Place and Duration of Study: Department of Surgery, National Institute of Medical Sciences (NIMS), Tertiary Care Teaching Hospital Jaipur, Rajasthan, between Feb 2019 and July 2019.
Methodology: The information was gathered in a predesigned performa from the clinical case sheets, drug charts of patients. Descriptive statistics were applied to the gathered information and dissected utilizing Microsoft Excel programming.
Results: A total of 190 prescriptions were collected of which 995 drugs were prescribed. The total number of antibiotics in prescription was found to be 263. The percentage of antibiotics was found to be 88.42% which was found to be higher on comparing with the WHO marker. Various class of antibiotics was prescribed in which cephalosporin with a total of 120 (45.62%) followed by penicillin 33 (12.54%), macrolide 1 (0.38%) fluoroquinolones 23 (8.75%), nitroimidazole 39 (14.82%), aminoglycoside 38 (14.44%) and other classes 9 (3.45%).
Conclusion: The adequacy of anti-microbial is undermined by the worldwide ascent in bacterial resistance and antimicrobial resistance is currently perceived as a significant medical issue. The study shows that the pattern of antibiotics was found to diverge from the WHO recommendation and also practice was lacking in terms of selection of antibiotics as there was no culture sensitivity test was performed. There gives off an impression of being an urgent requirement for the improvement of recommending rules with regards to the use of antibiotic agents.
Keywords: Prescription, WHO indicator, antibiotics, culture sensitivity, resistance