Antioxidant, Cytotoxic and larvicidal Potential in Oxalis latifolia Kunth. Methanolic Leaf Extract
R. Gopi Krishnan
Department of Botany, School of Life Sciences, Periyar University, Periyar Palkalai Nagar, Salem – 636 011, India.
S. Murugesh *
Department of Botany, School of Life Sciences, Periyar University, Periyar Palkalai Nagar, Salem – 636 011, India.
*Author to whom correspondence should be addressed.
Abstract
Aims: The current work was analyzed in antioxidants, cytotoxicity and larvicidal potential were examined for O. latifolia methanolic leaf extract.
Methodology: Antioxidant assasy for Hydroxyl radical (H2O2). Cytotoxicity potential was studied against colon (HT-29). Culex quinquefasciatus (IVth instar) larvae was used for larvicidal test.
Results: Antioxidant and cytotoxicity exhibits significant activities with IC50 value of 442.94 µg/mL and also the cytotoxicity activity IC50 values of 50.00μg/mL for HT-29. Larval mortality against the larvae of Cx. quinquefasciatus showed best activity with LC50 09.50mg/L and LC90 28.72 mg/L.
Conclusion: Thus, this study proved that methanolic leaf extracts of O. latifolia have significant biological activities. Hence, it can be used for pharmacetutical applications.
Keywords: Larvicidal potential.HT-29, Cx. quinquefasciatus, H2O2