Clinical and Prognostic Value of Vascular Wall Elasticity in Pregnant Women with Arterial Hypertension: A Review

Natalia Yurievna Borovkova

Department of Hospital Therapy and General Medical Practice named after V. G. Vogralik Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian Federation 10/1, Minin and Pozharsky Sq., Nizhny Novgorod, Russia.

Svetlana Olegovna Kolobova

Department of Obstetrics and Gynecology, Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian Federation 10/1, Minin and Pozharsky Sq., Nizhny Novgorod, Russia.

Lyudmila Vasilievna Borovkova

Department of Obstetrics and Gynecology, Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian Federation 10/1, Minin and Pozharsky Sq., Nizhny Novgorod, Russia.

*Author to whom correspondence should be addressed.


Abstract

In recent years, the attention of many researchers around the world has been focused on studying the risks associated with the development of the pathological course of pregnancy in women with arterial hypertension (AH). The pathogenesis of gestational complications is complex and is largely associated with endothelial dysfunction, changes in the structure and properties of the vascular wall and a decrease in its elasticity. At the same time, at the present stage, a high prognostic value of the assessment of vascular elasticity in the development of cardiovascular disasters in patients with hypertension in the general population has been proved. In order to predict the risk of gestational complications early, it is promising to study the state of elasticity of the vascular wall, which will optimize the management of pregnancy and improve perinatal outcomes in pregnant women with hypertension. The literature search was carried out by  keywords using the Scopus, Web of Science, Cyber Leninka, RSCI (Russian Science Citation Index) systems.

Keywords: Review, pregnancy, arterial hypertension, endothelial dysfunction, vascular wall elasticity, risk prediction


How to Cite

Borovkova, N. Y., Kolobova, S. O. and Borovkova, L. V. (2021) “Clinical and Prognostic Value of Vascular Wall Elasticity in Pregnant Women with Arterial Hypertension: A Review”, Journal of Pharmaceutical Research International, 33(45B), pp. 153–161. doi: 10.9734/jpri/2021/v33i45B32792.