Normal Reference Range for Serum TSH, Free T4, Total T4, and Total T3 on Roche® Platforms in Basrah, Iraq
Nassar Taha Alibrahim
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq.
Samih Abed Odhaib
Thi-Qar Specialized Diabetes, Endocrine and Metabolism Center, Nasiriyah, Thi-Qar, Iraq.
Ali Hussain Alhamza
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq.
Ammar Mohammed Saeed Almomin
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq.
Ibrahim Abbood Zaboon
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq.
Rudha Naser Hussein
Najaf Specialized Diabetes and Endocrine Center, Najaf Health Directorate, Najaf, Iraq.
Muayad Baheer Kadhim
Misan Specialized Diabetes and Endocrine Center, Misan Health Directorate, Amarah, Misan, Iraq.
Adel Gassab Mohammed
Thi-Qar Specialized Diabetes, Endocrine and Metabolism Center, University of Thi-Qar, Nasiriyah, Thi-Qar, Iraq.
Dheyaa Kadhim Al-Waeli
Thi-Qar Specialized Diabetes, Endocrine and Metabolism Center, University of Thi-Qar, Nasiriyah, Thi-Qar, Iraq.
Hussein Ali Nwayyir
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq.
Haider Ayad Alidrisi
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq.
Ibrahim Hani Hussein
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq.
Mahmood Thamer Altemimi
Thi-Qar Specialized Diabetes, Endocrine and Metabolism Center, Nasiriyah, Thi-Qar, Iraq.
Husam Jihad Imran
Misan Specialized Diabetes and Endocrine Center, Misan Health Directorate, Amarah, Misan, Iraq.
Abbas Ali Mansour *
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq.
*Author to whom correspondence should be addressed.
Abstract
Background: Thyroid function tests are mandatory in clinical practice because symptoms and signs are not reliable to discriminate between various types of thyroid disease.
Aim: The aim of this study was to determine assay-specific reference range for serum free T4, total T4, total T3 and TSH among healthy non-pregnant adult cohort for Roche® platforms in Basrah (Southern Iraq) from single laboratory in a tertiary center using indirect approach of the available data.
Methods: A Cross sectional study for non-pregnant adults 19 years and above. Sera were analyzed by using cobs e411 for thyroid functions tests.
Results: Total enrolled persons were 10,078. The 95% reference intervals for TSH were 0.20-6.50 μIU/mL, which increased with age though not linear, for free T4 were 0.8-1.70 ng/dL, for total T4 were 3.78-15.33 μg/dL, and for total T3 were 0.80-2.50 ng/mL.
Colcusion: Cobs e411(Roche® analytical platform) analyzer reference range for thyroid function cannot be applied for Iraqi population .
Keywords: Thyroid hormones, reference intervals, Roche® analytical platform