An Overview in the Management of Lumbar Degenerative Disc Diseases: Review Article
Abdulmalik B. Albaker *
Consultant Orthopaedic at Majmaah University, 11952, Saudi Arabia.
Saadah Abdulrahim Younis
Taibah University, Saudi Arabia.
Badr Eyad Hafiz
Taibah University, Saudi Arabia.
Hanan Osama Abuseer
Taibah University, Saudi Arabia.
Abrar Hasan Bukhamseen
Imam Abdulrahman Bin Faisal University, Saudi Arabia.
Faisal Saeed A. Al-Ghamdi
Tabuk University, Saudi Arabia.
Ibrahim Ahmed J. Albalawi
Tabuk University, Saudi Arabia.
Yasir Salah Hamed Aljohani
Taibah University, Saudi Arabia.
Daher Mushref Daher Alshehri
King Khalid University, Saudi Arabia.
Fahad Ali Ahmed Alzahrani
Bisha university, Saudi Arabia.
Ayman Dhaifallah A. Alamri
Bisha university, Saudi Arabia.
Raghad Khalid Alsherbi
Taif University, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
The degenerative disease of the intervertebral disc and back pain are chronic conditions that are caused by several factors and represent an important cause of morbidity and mortality in everyday clinical practice. The study aims to summarize the updated evidence regards epidemiology, pathophysiology, clinical manifestation, diagnosis, and management of degenerative disc diseases. The incidence of low back pain, which is the main symptom in Intervertebral Disc (IVD) disease, varies widely among different reports. It is the fifth most common cause for the visit to the doctor and affects 7.6 to 37% of patients. IVD degeneration is attributed to a complex interplay between environmental and genetic factors. DDD is a process that includes a progressive decrease in disk nutrient supply and changes in extracellular matrix (ECM) composition, which weakens the tissue strength and alters the cell metabolism.Degenerative lumb disc disease patients typically present with mechanical lower back pain, which is worse on forward flexion and when carrying heavy load. The pain is relieved with rest. Diagnosis of DDD is done by various methods, computed tomography (CT) scan, magnetic resonance imaging (MRI), and provocative discography. These methods should be used in conjunction with the patient history, physical examination and specific biomarker to monitor the response to treatment. There are three major lines of management of DDD; Treatment Options for Relief of Pain in Conservative Therapy.Treatment with Aims of Restoration, Repair, and Regeneration of Intervertebral Disc Diseases: Molecular Therapy. Reconstructive Strategies: Percutaneous Intervertebral Disc Techniques. Definitive Treatment for Intervertebral Disc Diseases :( surgical management).
Keywords: Lumbar degeneration, lumbar disc diseases, management, lower back pain