Anti-Cancer Activity of Andrographolide: A Review

Vishwanadham Yerragunta *

Department of Pharmacy, University College of Technology, Osmania University, Hyderabad, Telangana, India.

Kavita Waghray

Department of Pharmacy, University College of Technology, Osmania University, Hyderabad, Telangana, India.

. Shivraj

Department of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana, India.

N. J. P. Subhashini

Department of Chemistry, University College of Science, Osmania University, Hyderabad, Telangana, India.

*Author to whom correspondence should be addressed.


Abstract

Andrographolide, is a chemical compound obtained from the Andrographis paniculata (Family- Acanthaceae), maybe a diterpene lactone ring is responsible for various biological activities like anti-inflammation, anti-microbial anti-cancer, anti-obesity, anti-diabetes, anti-oxidant immunomodulatory, antiseptic, hypolipidemic, cardioprotective, hepatoprotective, neuroprotective effects and other biological activities. In Current research activities worldwide to exhibit the beneficial role of Andrographolide are continuously enriching the therapeutic arsenal of this important Phyto molecule. For this purpose, several databases were accustomed explore for the anticancer/cytotoxic effects of the andrographolide in pre-clinical and clinical studies. During this report, an attempt has been given to spotlight the research findings, related to therapeutic potentials and up-to-date development within the pharmacological activities of andrographolide. Andrographolide is often one of the potential agents within the treatment of cancer.

Keywords: Andrographolide, Andrographis paniculata, anti-cancer activity


How to Cite

Yerragunta, V., Waghray, K., Shivraj, . and Subhashini, N. J. P. (2021) “Anti-Cancer Activity of Andrographolide: A Review”, Journal of Pharmaceutical Research International, 33(43B), pp. 1–9. doi: 10.9734/jpri/2021/v33i43B32519.