Methods of Diagnosis a Preferential Advantage in COVID-19: A Mini Review
Neha Saini
Symbiosis Centre for Nano Science and Nano Technology, Symbiosis International (Deemed University), Lavale, Pune 412115, Maharashtra, India.
Prem Pandey
Symbiosis Centre for Nano Science and Nano Technology, Symbiosis International (Deemed University), Lavale, Pune 412115, Maharashtra, India.
Mandar Shirolkar
Symbiosis Centre for Nano Science and Nano Technology, Symbiosis International (Deemed University), Lavale, Pune 412115, Maharashtra, India.
Atul Kulkarni
Symbiosis Centre for Nano Science and Nano Technology, Symbiosis International (Deemed University), Lavale, Pune 412115, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
Humanity is going through never seen before health crisis due to the outbreak of novel coronavirus or Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). There are 24.02 million cases and 0.82 million deaths worldwide as of 26th August 2020 due to deadly infection of COVID-19. The disease has been spreading exponentially (R-naught number: 3) and has challenged even the best healthcare infrastructure in the world. With the progression of the disease, the countries shifted the focus from cure to diagnosis and containment to flatten the curve. The review shows that the disease is spreading exponentially while the resources are still limited. We focus upon the probable vectors of the virus, different diagnostic methods with advantages & limitations, and the way forward. This review article covers the different diagnostic methods with more advantages, limitations, and the future sneak-peek into the forthcoming developments for the diagnostic processes such as RT-PCR (Reverse Transcription Polymerase chain reaction).
Keywords: SARS-CoV-2, serology, RT-PCR, COVID-19, CT-scan, X-ray, coronavirus and ultrasound