Journal of Pharmaceutical Research International

Abhrasindoora is a unique mercurial formulation as a herbo-bio-mineral metallic compound which is mentioned under Kupipakwa Rasayana Prakarana in Rasendra Sambhava. There are four formulations are mentioned with the name of Abhrasindoora, amongst them one in Rasendra Shambhava and three in Rasayogasagara. In this review article we have focused on the specific method mentioned in Rasendra Sambhava, which is a combination of Dhanyabhraka, Shodhita Parada (Mercury), Shodhita Gandhaka (Sulphur) in equal proportion (1:1:1). Its method of preparation initiates with the Kajjali formation followed by impregnation of Latex of Calotropis procera (QS) and freshly expressed arial root juice of Ficus bengalensis (QS) and cooking into mud smeared seven layered glass bottle using sand bath heating system. Specific heating pattern consisting of mild (120⁰C-250⁰C) moderate (250⁰C-450⁰C) and intense (450⁰C-650⁰C) heat should be maintained for preparation of Abhrasindoora. Previous pharmaceutical study done by Dr. Jyoti B. (2018) had yielded approximately 28% bright red color Abhrasindoora. In Rasayogasagara, bhasmikarana process is mentioned for preparation of Abhrasindoora which is not appropriate as per current trend. Hence, Rasendra Sambhava method is appropriate to prepare Abhrasindoora. This formulation has broad spectrum activity along with suitable adjuvants. The therapeutic indications are Cough, Bronchial Asthma, Fever etc. This herbo-bio-mineral metallic compound is quick acting, low dose, highly stable, good palatability and helps to treats chronic ailments.