Updates in Diagnosis and Managements of Polymyositis: Simple Review
Laila Abdullah S. Alanazi *
University of Tabuk, Saudi Arabia.
Abdullah Mohammed A. AL Madshush
University of Tabuk, Saudi Arabia.
Omniyyah Mohammed S. Alatawi
University of Tabuk, Saudi Arabia.
Asmaa Hamed M. Albuhairy
University of Tabuk, Saudi Arabia.
Jomana Khalid M. Aljohani
University of Tabuk, Saudi Arabia.
Asmaa Muslim Alfahimani
University of Tabuk, Saudi Arabia.
Jalawi Talal A. Alotaibi
University of Tabuk, Saudi Arabia.
Abrar Atallah O. Alatawi
University of Tabuk, Saudi Arabia.
Mohammed Ibrahim F. Bin Ibrahim
University of Tabuk, Saudi Arabia.
Saud Mohammed S. Alrofydi
King Khalid University, Saudi Arabia.
Marwan Fahad H. altemani
King Salman Armed Force Hospital, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Idiopathic inflammatory myopathies (IIMs) includes an unusual group of acute, chronic, and subacute developed diseases of skeletal muscle characterized by moderate to severe muscle weakness and inflammation.Polymyositis is generally considered to be a prototypic T cell-mediated autoimmune myopathy, while DM was traditionally associated with a humoral-driven microangiopathy, though the putative autoantibodies and their targets have yet to be identified, and there is increasing evidence implicating the type I interferon pathway in the pathogenesis of the disease. Women between the ages of 50 and 70 are the most typically affected. Proximal muscular weakness is the most common clinical symptom. Inflammatory arthritis, Raynaud's phenomenon, myocarditis, and interstitial lung disease are all examples of extramuscular involvement. In this review, we overview updates in diagnosis and managements of polymyositis.
Keywords: Polymyositis, proximal muscular weakness, idiopathic inflammatory myopathies (iims), arthritis