Study on Serum Zinc Levels and Vitamin a Levels in Tuberculosis Patients
Gangaram Bhadarge
Department of Biochemistry Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences Sawangi (Meghe) Wardha-442001, India.
Nandkishor Bankar *
Department of Microbiology Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha, India.
Sudhir Singh
Department of Dermatology Datta Meghe Medical College, Shalinitai Meghe Hospital and Research Centre (Datta Meghe Institute of Medical Sciences), India.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Tuberculosis, an infectious disease caused by the bacteria Mycobacterium tuberculosis (MTB), is also a major cause of death in humans around the world. According to a World Health Organization (WHO) survey, MTB infects one-third of the world's population, with 9.6 million new tuberculosis (TB) infections and 1.5 million deaths confirmed this in 2021
Aim: study of serum zinc levels and vitamin a levels in tuberculosis patients.
Materials and Methods: This study included 40 newly diagnosed PTB patients of both sex with the age group of 18-60.Time period of this study was from September 2020 to Арril 2021 а nоn-rаndоmised соntrоlled trial was involved.
Result: There was a strong correlation between serum zinc and vitamin A levels P < 0.01) Hb, P < 0.01) and serum albumin levels P < 0.01) were also strongly correlated with the vitamin A levels; however, WBC P < 0.01) and ESR P < 0.01) were negatively correlated with the vitamin A levels.
Conclusion: In view of the above, the patient's nutritional status may be the most important determinant of infection tolerance. Zinc deficiency can have an indirect impact on Vitamin A metabolism by reducing the levels of circulating protein. Because of this, the addition of zinc in combination with vitamin A may be helpful in achieving the disease status.
Keywords: MTB, Vit-A, Zinc, Retinol, Micronutrient