Effect of Triclosan and Sodium Monofluorophosphate on Plaque Reduction

Seema Soomro

Community Dentistry Department, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

Munir Ahmed Banglani

Oral Biology Department, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

Parveen Memon

Oral Biology Department, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

Mahwish Memon

Operative Dentistry Department, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

Abdul Qadir Khan Dall

Operative Dentistry Department, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

Salman Shams *

Oral Medicine Department, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

*Author to whom correspondence should be addressed.


Abstract

Objective:  The aim of the study is to compare the clinical efficacy between two ingredient Triclosan and sodium monofluorophosphate on plaque accumulation.

Material and Methodology: This cross section study was carried out in school (Govt Girls High School Kotri). Total 100 school children were selected, between age ranges 13–16 years, which were divided in to two groups (group A & B) according to dentifrice given.

Group A: Toothpaste containing the active ingredient 0.3% Triclosan.

Group B: Toothpaste containing 0.8% sodium monofluorophosphate.                     

All patients were examined clinically for assessment using the Plaque index (PI) at follow up periods every week. Plaque was evaluated by using the silness-loe index.  Oral examination for dental plaque assessment was carried out at the start of the study and the children were follow up to 10 weeks. Data were analyzed by SPSS 16 version and one-way ANOVA test.

Result: Triclosan toothpaste users experienced significant reduction in plaque accumulation as compared to the sodium monofluorophosphate toothpaste users.

Conclusion:  At 3-weeks, Triclosan provided statistically significantly greater reductions than sodium monofluorophosphate in plaque reduction.

Keywords: Plaque reduction, sodium monofluorophosphate, triclosan


How to Cite

Soomro, S., Banglani, M. A., Memon, P., Memon, M., Dall, A. Q. K. and Shams, S. (2021) “Effect of Triclosan and Sodium Monofluorophosphate on Plaque Reduction”, Journal of Pharmaceutical Research International, 33(34A), pp. 154–159. doi: 10.9734/jpri/2021/v33i34A31835.