Primary Malignant Fibrous Histiocytoma of Proximal Humerus with Pathological Fracture- Case Report
Malkesh D. Shah
Department of Orthopaedics, Smt. B. K. Shah Medical Institute and Research Center, Sumandeep Vidyapeeth Deemed to be University, India.
Ajinkya Arun Naik *
Department of Orthopaedics, Smt. B. K. Shah Medical Institute and Research Center, Sumandeep Vidyapeeth Deemed to be University, India.
Sai Sabharish Reddy
Department of Orthopaedics, Smt. B. K. Shah Medical Institute and Research Center, Sumandeep Vidyapeeth Deemed to be University, India.
Sarvang M. Desai
Department of Orthopaedics, Smt. B. K. Shah Medical Institute and Research Center, Sumandeep Vidyapeeth Deemed to be University, India.
*Author to whom correspondence should be addressed.
Abstract
Malignant fibrous histiocytoma (MFH) is a tumor of late adulthood that occurs in men more commonly than women. Proximal humerus involvement in PMFH is comparatively rare. A 45 year old female presented with complain of pain and mild swelling over the left shoulder with restricted range of movement since 15 days. Radiography of the affected part was suggestive of an osteolytic eccentric lesion with a pathological fracture. A trucut needle biopsy showed minimal tumour tissue with abundant necrosis and showed giant cells with pleomorphic mononuclear cells. So intralesional curettage followed by osteosynthesis with PHILLOS plating and bone cementing was done. Intra operative specimen sent for histopathological examination showed presence of fibroblast cells arranged in storiform pattern s/o MFH along with occasional multinucleated giant cells. Postoperatively patient was started with adjuvant chemotherapy. Patient had good results functionally and clinically with no signs of recurrence till follow up of 1.5 years.
Keywords: Malignant fibrous histiocytoma (MFH), proximal humerus pathological fracture with osteolytic lesion, malignant fibrous histiocytoma of bone