Frequency of Haemoglobin Genotype Variants, ABO and Rh ‘D’ Antigen among Madonna Undergraduates of South East Origin, Nigeria
Richard Eze
Department of Medical Laboratory Science, Madonna University, Elele, Rivers State, Nigeria.
Emmanuel Ifeanyi Obeagu
*
Department of Medical Laboratory Science, Madonna University, Elele, Rivers State, Nigeria and Department of Medical Laboratory Science, Imo State University, Owerri, Imo State, Nigeria.
Arvin Nwakulite
Department of Medical Laboratory Science, Madonna University, Elele, Rivers State, Nigeria.
C.C.N. Vincent
Department of Nursing Science, Imo State University, Owerri, Imo State, Nigeria.
Sylvester Ogbonna Ogbodo
Department of Medical Biochemistry, Faculty of Basic Medical Science, College of Medicine, Enugu State University of Science and Technology, Enugu State, Nigeria.
Adaobi Maryann Ibekwe
Department of Nursing Science, Nnamdi Azikiwe University, Nnewi Campus, Nnewi, Anambra State, Nigeria.
Chukwuma J. Okafor
Department of Pathology and Biochemistry, State University of Zanzibar, Tanzania.
Ejike Felix Chukwurah
Department of Haematology and Immunology, Faculty of Clinical Medicine, Ebonyi State University, Abakaliki, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Haemoglobin genotype variants, ABO and Rh blood groups are known to vary from one population to another. Standard electrophoretic and haemagglutination techniques were employed in testing the blood samples. Of the 150 test subjects screened, HbAA in the male subjects were 58(48.0%) and 63(52.0%) in the female counterparts. The frequency of distribution of HbAA, HbAS, and HbSS in the subject were 121 (80.7%), 28 (18.7%) and 1 (0.6%). Also HbAS in the female was 16(57.1%) while in male subjects was 12(42.9%). Blood group A (41.7%), group B(21.7%), group AB(28.6%) and group O(57.1%) were results for male subjects as against Group A(58.3%), Group B(78.3%), Group AB (71.4%) and Group O(42.9%) respectively in the female subjects.90% were Rh ‘D’ positive while 10% were Rh ‘D’ negative. Knowledge of the distribution of ABO, Rh ‘D’ blood groups and haemoglobin genotype variants in any population is useful in health care planning, medical diagnosis and targeting the population that need counseling. If such information is well managed it can make a difference in the quality of decisions that individuals will make especially as it concerns marriage, blood transfusion and other medical demands.
Keywords: Haemoglobin genotype variant, ABO, Rh ‘D’ antigen