Estimation of Alanine Transaminase (ALT), Alkaline Phosphate (ALP) and Aspartate (AST) Irrespective of Dietary Supplementation, Body Mass Index and Nature of Exercise

Alamgir Khan *

Department of Sports Sciences and Physical Education, University of the Punjab Lahore, Pakistan.

Muhammad Zafar Iqbal Butt

Department of Sports Sciences and Physical Education, University of the Punjab Lahore, Pakistan.

Abdul Manan

Department of Economics, Gomal University, Dera Ismail Khan, KPK, Pakistan.

Ejaz Asghar

Department of Sports Sciences and Physical Education, ISRA University Islamabad Pakistan.

Muhammad Jamil

Punjab Highway Patrolling Police Lahore Region, Pakistan.

Samiullah Khan

Gomal Center of Biochemistry and Biotechnology, Gomal University, Dera Ismail Khan, KPK, Pakistan.

*Author to whom correspondence should be addressed.


Abstract

Purpose: This research study was conducted for the assessment of liver enzymes i.e. Alanine Transaminase (ALT), Alkaline Phosphate (ALP) and Aspartate (AST) irrespective of dietary supplementation, body mass index and nature of the exercise.

Methods: A randomized control trails were taken and thus Sixty (60) subjects ageing 20 to 30 years, (Twenty (20) from low-intensity exercise (EXG-II), Twenty (20) from high-intensity exercise (EXG-III) and Twenty (20) subjects as a control group (CG-III) were included in the study by using International Physical Activity Scale (IPAQ).5ml blood samples were collected from the subjects for the determination of liver functions and blood redox status. Each blood sample was marked with a separate identification mark. After the collection of blood samples, three particular liver enzymes tests i.e. ALT, ALP and AST were performed. The results of the samples test proceeded through the Statistical Package for Social Science (SPSS) Version 23.

Results: The P-Value of the low-intensity exercise group (EXG-II) in term of ALT was less than the high-intensity exercise group ( EXG-III) ( p >.05), The P-Value of the low-intensity exercise group (EXG-II) in term of ALP was less than the high-intensity exercise group ( EXG-III) ( p >.05). The P-Value of low-intensity exercise group (EXG-II) in term of AST was less than high-intensity exercise group (EXG-III) (p >.05).

Conclusion: Based on findings, it was concluded that low-intensity exercise with dietary supplementation positively affects the functions of the liver i.e. Alanine Transaminase (ALT), Alkaline Phosphate (ALP) and Aspartate (AST) as compared to high-intensity exercise. Similarly high-intensity exercise with dietary supplementation also positively influence as compared to performers of high-intensity exercise without dietary supplementation.

Keywords: Low-intensity exercise, high-intensity exercise, ALT, ALP, AST, BMI, dietary supplementation


How to Cite

Khan, A., Butt, M. Z. I., Manan, A., Asghar, E., Jamil, M. and Khan, S. (2021) “Estimation of Alanine Transaminase (ALT), Alkaline Phosphate (ALP) and Aspartate (AST) Irrespective of Dietary Supplementation, Body Mass Index and Nature of Exercise”, Journal of Pharmaceutical Research International, 33(28B), pp. 33–44. doi: 10.9734/jpri/2021/v33i28B31536.

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