In-vitro Antibacterial Activity of Acacia Nilotica against Lactobacillus casei
Abid Khan
Department of Pharmacology, Faculty of Pharmacy, Ziauddin University, Karachi Pakistan.
Muhammad Owais Ismail
Department of Pharmacology, Faculty of Health Sciences, Ziauddin University, Karachi Pakistan.
Mirza Tasawer Baig *
Department of Pharmacy Practice, Faculty of Pharmacy, Ziauddin University, Karachi Pakistan.
Sadia Suri Kashif
Department of Pharmacology, Faculty of Pharmacy, Ziauddin University, Karachi Pakistan.
Aisha Jabeen
Department of Pharmacology, Faculty of Pharmacy, Ziauddin University, Karachi Pakistan.
Shumaila Sheikh
Bibi Aseefa Dental College, Larkana, Pakistan.
Uzma Shahid
Surecell Australian Stem Cell Clinic Karachi, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Background: The role of Ethno-pharmacology is important to discover the new biologically active compounds. The process usually starts with searching of useful plants from different records to the development of methods for the industrial production of drugs. World Health Organization (WHO) states that more than 80% of population of the world makes the use of plants for the treatment of diseases. The extensive use of plants for therapeutic purposes has the history of centuries. Herbal pharmaceuticals have treated many diseases and confirmed the importance of medicinal plants on curative ground. The aim of this study was to evaluate in-vitro antibacterial activity of traditionally used Acacia nilotica by aqueous and Ethanolic extraction, against Lactobacilli casei.
Methodology: Disc diffusion method for antimicrobial susceptibility testing was carried out according to the Kirby-Bauer method to assess the presence of antibacterial activities of Ethanolic and Aqueous extracts of Acacia nilotica, against Lactobacillus casei. Results: It was found that Ethanolic extracts have antibacterial activity which was close to the positive controls (standards) of the study; 2.5% Sodium hypochlorite and 2% Chlorhexidine.
Conclusion: it was concluded that Ethanolic extract of Acacia nilotica, possesses antibacterial activity against Lactobacillus casei.
Keywords: Antibacterial activity, acacia nilotica, lactobacillus casei, traditional medicine