Liquid Based Cytology versus Conventional Cytology for Evaluation of Cervical PAP Smear
Vishakha Chandwani
Department of Pathology, Sree Balaji Medical College & Hospital (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
K. Saraswathi
Department of Pathology, Sree Balaji Medical College & Hospital (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
G. Bheema Rao
Department of Pathology, Sree Balaji Medical College & Hospital (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
Vindu Sivastava *
Department of Pathology, Sree Balaji Medical College & Hospital (Affiliated to Bharath Institute of Higher Education and Research), Chennai, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
The cervix is the narrow inferior segment of the uterus which projects into the vaginal vault. Conventional cervical cytology is a simple, cost effective method that has been in use for more than 50 years and is still a highly effective cervical cancer screening procedure. Liquid-based, thin-layer preparation of cervical cytology specimens was a subsequent modification in technique. The present study was split-sample study was to compare Thin Prep Liquid-based Cytology with Conventional Pap Smear, relying on a laboratory with long term experience of the former. In our study most of the Conventional preparations showed cell overlapping, inflammatory cells, blood and mucus that obscure the epithelial cell morphology which was much reduced in Liquid based preparations.
Keywords: Cervix, cervical cancer, pap smear, thin prep liquid-based cytology, pap smearthin prep liquid-based cytology