Molecular Evaluation of COVID-19 in Pandemic Era
Diksha Kumari
Department of Molecular Biology and Genetic Engineering, Bihar Agricultural University, Sabour, Bhagalpur-813210, Bihar, India and Department of Plant Physiology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi-221005, UP, India.
Bishun Deo Prasad *
Department of Molecular Biology and Genetic Engineering, Bihar Agricultural University, Sabour, Bhagalpur-813210, Bihar, India.
Padmanabh Dwivedi
Department of Plant Physiology, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi-221005, UP, India.
Sangita Sahni
Department of Plant Pathology, TCA, Dholi, Dr. Rajendra Prasad Central Agricultural University, Dholi, Pusa, Bihar, India.
*Author to whom correspondence should be addressed.
Abstract
COVID-19 (SARS-CoV-2) has recently emerged as an ongoing pandemic disease or probably syndemic and became the latest threat to global health. The main route of transmission of virus droplet start with respiratory problems coughing, sneezing, fever during infection period, which may end up with death, if not treated. Many emerging epidemiological factors have made COVID-19 as global alarming disease. To control the outbreak of COVID-19, a critical management along with quarantine measure is applicable, which requires early detection of infection. The early detection of COVID-19 infection is playing a vital role in controlling of progression of illness and limiting viral spread within the population. Therefore, reliable, highly specific and sensitive diagnosis techniques are necessary for its early detection. Among several detection techniques, qRT-PCR is the rapidly employed, sensitive and widely accepted technique. In present review, different molecular techniques with emphasis on qRT-PCR for early diagnosis of emerging COVID-19 will be discussed.
Keywords: COVID-19, SARS-CoV-2, qRT-PCR.