Comparison of Submucosal Injection of Dexamethasone and Triamcinolone Acetonide for Control of Postoperative Pain after Impacted Mandibular Third Molar Surgery- A Prospective Randomized Controlled Trial
Yandeti Srinivasulu
Department of Oral and Maxillofacial Surgery, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, 162, Poonamallee High Road, Chennai 600077, Tamil Nadu, India.
Abdul Wahab
Department of Oral and Maxillofacial Surgery, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, 162, Poonamallee High Road, Chennai 600077, Tamil Nadu, India.
P. Senthil Murugan *
Department of Oral and Maxillofacial Surgery, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, 162, Poonamallee High Road, Chennai 600077, Tamil Nadu, India.
*Author to whom correspondence should be addressed.
Abstract
The aim of the study was to compare the efficacy of submucosal injection of dexamethasone and triamcinolone acetonide on postoperative pain, swelling, occurring after impacted mandibular third molar surgery. A total of 150 patients with asymptomatic, unilateral, impacted mandibular third molar, and without any systemic disease were included in this study. Patients were divided into three groups randomly, one group dexamethasone, and the second group triamcinolone acetonide third group placebo. Dexamethasone and triamcinolone acetonide were injected into submucosa at about 0.5 cm to 1 cm above the surgical area submucosally. Pain evaluation was performed by visual analog scale (VAS).There were statistically significant differences between the three groups on the different days of the postoperative period. The effect of triamcinolone acetonide works postoperatively and the effect of triamcinolone acetonide on trismus and pain was better than other groups. There was no significant difference between the effects of dexamethasone and triamcinolone acetonide regarding postoperative complications. The submucosal injection of dexamethasone and triamcinolone acetonide might be an effective treatment following impacted mandibular third molar surgery, and triamcinolone acetonide could be applied as an alternative to dexamethasone for reducing pain post operatively for impacted mandibular third molar surgery.
Keywords: Dexamethasone, triamcinolone, mandibular, molar, synthetic steroids, maxillofacial surgery.