Comparison of Two Irrigation Solutions in the Surgical Removal of the Mandibular Third Molars- A Randomized Trial

P. Aditya Reddy

Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu-600077, India.

P. U. Abdul Wahab

Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu-600077, India.

V. Jagadish

Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu-600077, India.

P. Senthil Murugan *

Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, Tamil Nadu-600077, India.

*Author to whom correspondence should be addressed.


Abstract

Aim: To evaluate the effect of postoperative irrigation with chlorhexidine saline irrigation and metronidazole saline irrigation on non-inflammatory complications after the extraction of lower third molar under local anesthesia.

Materials and Methods:  In this study a total of 120 patients with age range 18-80 years who had impacted tooth which required surgical removal were included. The patients were separated into two groups using Block Randomization to avoid sampling bias. Group A and Group B had 60 patients each. Group A patients were irrigated with 1% Chlorhexidine Saline and Group B patients were irrigated with 1% Metronidazole Saline during the surgical removal of their mandibular third molars. The patients were measured for the pain, swelling and checked for dry socket after 7 days of procedure.

Results: The mean age of the patient was 28.08 + SEM years. Out of three parameters (Pain, Swelling, Dry Socket) assessed, only alveolar osteitis showed a statistical significant difference between 1% Metronidazole and 1% Chlorhexidine with p value 0.041(>0.05). Trismus and pain did not differ significantly (p>0.05) in the two groups with p-values of 0.431 for trismus and 0.750 for pain.

Conclusion: Metronidazole had better efficacy in alveolar osteitis, while in the other parameters viz, pain and mouth opening there was no difference in the two treatments.

Keywords: Complications, dry socket, impacted teeth, irrigation, trismus.


How to Cite

Reddy, P. A., Wahab, P. U. A., Jagadish, V. and Murugan, P. S. (2020) “Comparison of Two Irrigation Solutions in the Surgical Removal of the Mandibular Third Molars- A Randomized Trial”, Journal of Pharmaceutical Research International, 32(28), pp. 28–35. doi: 10.9734/jpri/2020/v32i2830868.