Assessment of Neonatal Respiratory Distress Incidences with Causes, Mortality and Morbidity in a Tertiary Care Hospital
Kanwal Baloch
Shaheed Mohtarma Benazir Bhutto Medical University, Pakistan.
Delijan Mugheri
Shaheed Mohtarma Benazir Bhutto Medical University, Pakistan.
Abdul Majeed Soomro
Pir Abdul Qadir Shah Jillani Institute of Medical Science Gambat, Pakistan.
Wasim Sarwar Bhatti
Pir Abdul Qadir Shah Jillani Institute of Medical Science Gambat, Pakistan.
Muhammad Khan
Pir Abdul Qadir Shah Jillani Institute of Medical Science Gambat, Pakistan.
Shafi Muhammad Wassan
Shaheed Mohtarma Benazir Bhutto Medical University, Pakistan.
Shumaila Usman
Department of Research, Ziauddin University Karachi, Pakistan.
Uzair Nisar
Faculty of Pharmacy, Ziauddin University Karachi, Pakistan.
Waseem Abbas Malhani *
Institute of Pharmacy Shaheed Mohtarma Benazir Bhutto Medical University, Pakistan.
Nadeem Baloch
Institute of Pharmacy Shaheed Mohtarma Benazir Bhutto Medical University, Pakistan.
Altaf Ali Mangi
Faculty of Pharmacy, Gomal University, DI Khan, Pakistan.
Saika Lashari
Department of Pharmacy, Shah Abdul Latif University, Khairpur, Pakistan.
Rashid Ali Arbani
Department of Pharmacy, Shah Abdul Latif University, Khairpur, Pakistan.
Sultan Othman Alolyan
College of Pharmacy, Taibah University, Saudi Arabia.
Shumaila Parveen Arain
Faculty of Pharmacy, University of Sindh, Jamshoro, Pakistan.
Sultan M Alshahrani
College of Pharmacy, Taibah University, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Background: The objective of this study conducted in a neonatal intensive care unit of a tertiary care hospital Larkana was to check the prevalence of respiratory distress in neonates and their morbidity and mortality associated with respiratory distress.
Methods: A retrospective analysis of neonates with the respiratory distress syndrome during the period of one year was evaluated. The prevalence, risk factors related with respiratory distress syndrome were compared on the basis of neonatal and maternal factors.
Results: The Majority of respiratory distress in our study, were due to Transient Tachypnea of newborn (TTN) 29.8%, RDS 22.1%, birth asphyxia 17%, and Meconium Aspiration Syndrome (MAS) 15.7%. Overall outcome of Neonatal Respiratory Distress was cure rate in 65.4%, Neonatal mortality rate 26.84% with highest mortality due to RDS and Sepsis and the morbidity rate is 7.7%. Conclusion: The TTN was the most common cause of respiratory distress in neonates. Mortality rate was 26.84% and was highest among the neonates with respiratory distress syndrome.
Keywords: Neonates, Respiratory Distress Syndrome (RDS), Transient Tachypnea of newborn (TTN), Meconium Aspiration Syndrome (MAS).