Solubility of Calcium Phosphate Crystallization In vitro in Presence of Basella rubra Deproteinized Concoction used in Non-codified Medicine for Urinary Stone
G. Ramu *
Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India.
S. K. Navanita
Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India.
Roan Ngoc Anh Huy
Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India.
B. Duraiswamy
Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India.
S. P. Dhanabal
Department of Pharmacognosy, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Tamilnadu, India.
*Author to whom correspondence should be addressed.
Abstract
The solubility of calcium phosphate crystallization in vitro by an deproteinized concoction of Basella rubra plant was investigated by weight reduction assay. Soluble oxalate of the plant are partially removed prior to extraction of plant material. The weight variation and dissolution results reveals that the concoction showed considerable increased activity at the highest concentration used. The results indicate that the calcium phosphate crystal inhibition activity exhibited by the plant material may be due to their calcium phosphate solubilising capacity of phytoconstituents present in them. Regular consumption of an concoction of our plant would be helpful in calculi prophylaxis.
Keywords: Calculi, Basella rubra, concoction, plant organs, phosphate inhibition.