Kewda (Pandanus odorifer) Flower Derived Phytochemicals against Salutaridine Reductase of Hepatitis Virus Causing Hepatitis A
Pratyasa Pradhan
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Nibedita Patra
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Subhadra Manjari Parida
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Hrudaya Ballava Dash
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Bhagyeswari Behera
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
Srimay Pradhan *
School of Applied Sciences, Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Pandanus odorifer plant extract is traditionally used to cure Hepatitis A. It is caused by Hepatitis virus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 1, 2, 3-benzene triol can effectively deactivate the salutaridine reductase enzyme thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Pandanus odorifer, hepatitis virus, hepatitis A.