Trigonella foenum-graecum Derived Phytochemicals against Tuberculosis
Bidyashree Tripathy
Centurion University of Technology and Management, Odisha, India.
Elina Sahoo
Go to Market Laboratory, Gram Tarang, Odisha, India.
Sidhartha Ray
Centurion University of Technology and Management, Odisha, India.
Soumya Jal
Centurion University of Technology and Management, Odisha, India.
Dipankar Bhattacharyay *
Centurion University of Technology and Management, Odisha, India. and Go to Market Laboratory, Gram Tarang, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Trigonella foenum-graecum plant extract are traditionally used to cure Tuberculosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that this plant extract can effectively deactivate the dihydrofolate reductase enzyme thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Trigonella foenum-graecum, tuberculosis