Buddleja asiatica Lour. Derived Phytochemicals against Staphylococcus aureus Causing Skin Diseases
Sasmita Patra
Centurion University of Technology and Management, Odisha, India.
Sarthak Siddhant Mishra
Centurion University of Technology and Management, Odisha, India.
Manaranjan Behera
Centurion University of Technology and Management, Odisha, India.
Ruchi Samparna Sahoo
Centurion University of Technology and Management, Odisha, India.
Swetanginee Gouda
Centurion University of Technology and Management, Odisha, India.
Sushree Susmita Palei
Centurion University of Technology and Management, Odisha, India.
Gyanranjan Mahalik *
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Buddleja asiatica plant extract are traditionally used to cure skin diseases. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that lignoceric acid can effectively deactivate the L-lactate dehydrogenase enzyme thereby interrupting the life cycle of the organism.
Keywords: Buddleja asiatica, phytochemical, Staphylococcus aureus, skin diseases