Bixa orellana Derived Phytochemicals against Entamoeba histolytica Causing Dysentery
Sonali Parida
Centurion University of Technology and Management, Odisha, India.
Jogesh Kumar Nayak
Centurion University of Technology and Management, Odisha, India.
Anindita Jena
Centurion University of Technology and Management, Odisha, India.
Arsia Tabish
Centurion University of Technology and Management, Odisha, India.
Archita Sahoo
Centurion University of Technology and Management, Odisha, India.
Ananya Pani
Centurion University of Technology and Management, Odisha, India.
Rukmini Mishra *
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Bixa orellana plant extract are traditionally used to cure Dysentery. It is caused by Entamoeba histolytica. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that benzoin acid can effectively deactivate the alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Bixa orellana, Entamoeba histolytica