Anti-inflammatory Potentials of Fibraurea tinctoria Leaves Extract in Experimental Rats or Animals
Fahad I. Al-Saikhan *
College of Pharmacy, Prince Sattam Bin Abdulaziz University, P.O.Box 173, Al-Kharj, 11942, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
The activity of the hydroalcoholic extract of Fibraurea tinctoria leaves and anti-inflammatory was investigated. We utilized rats for which oedema was induced by carrageenan. The extract of Fibraurea tinctoria leaves was administered orally at doses of 100, 200 and 400 mg/kg. Paw oedema was significantly minimized using all prepared doses of the extract administered. The 400 mg/kg dose producing the highest oedema reduction. The Percent Inhibition with hydroalcoholic extract of Fibraurea tinctoria and Indomethacin were 67.6% and 68.49% respectively. We concluded that this study has established the anti-inflammatory activity of hydroalcoholic extract of Fibraurea tinctoria leaves. I believe the results justify the traditional uses of the plant in the treatment of wounds and inflammation.
Keywords: Anti-inflammatory, Fibraurea tinctoria, carrageenan, hydroalcohol