Guava Seeds Derived Phytochemicals against Dysentery

Lopita Mishra

Centurion University of Technology and Management, Odisha, India.

Barsha Nayak

Centurion University of Technology and Management, Odisha, India.

Bibhu Prasad Mishra

Centurion University of Technology and Management, Odisha, India.

Dipankar Bhattacharya

Centurion University of Technology and Management, Odisha, India.

Mukundjee Pandey *

Centurion University of Technology and Management, Odisha, India.

*Author to whom correspondence should be addressed.


Abstract

Phytochemicals are the secondary metabolites that are known as nonnutritive but extremely beneficial for the defensive system for the organism. These phytochemicals can be obtained from all the plants and they play a major role in curing differnt diseases. The extract of the guava seed contains various phytochemicals that can cure the disease like dysentery, caused by the protozoa parasite, namely Entamoeba histolytica. “Biovia Discovery Studio” was used for the molecular docking process. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Heptadecanoic acid can effectively deactivate the alcohol dehydrogenase enzyme further inhibiting the biological process of the causative organism.

Keywords: Heptadecanoic acid, Guava, Entamoeba histolytica


How to Cite

Mishra, L., Nayak, B., Mishra, B. P., Bhattacharya, D. and Pandey, M. (2020) “Guava Seeds Derived Phytochemicals against Dysentery”, Journal of Pharmaceutical Research International, 32(7), pp. 124–127. doi: 10.9734/jpri/2020/v32i730522.