Eclipta alba L. Derived Phytochemicals against Escherichia coli Causing Diarrhea
Krishna Rani
Centurion University of Technology and Management, Odisha, India.
Aischarya Mohanty
Centurion University of Technology and Management, Odisha, India.
Sagarika Parida
Centurion University of Technology and Management, Odisha, India.
Manisha Mohanty *
Centurion University of Technology and Management, Odisha, India.
Subhashree Sahu
Centurion University of Technology and Management, Odisha, India.
Sanchayita Nayak
Centurion University of Technology and Management, Odisha, India.
Sutapa Mohanty
Centurion University of Technology and Management, Odisha, India.
*Author to whom correspondence should be addressed.
Abstract
Phytochemicals from Eclipta alba L. plant extract are traditionally used to cure Diarrhea. It is caused by Escherichia coli. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Pentadecanone can effectively deactivate the alcohol dehydrogenase enzyme (protein database code 4GKV) thereby interrupting the life cycle of the organism.
Keywords: Phytochemical, Eclipta alba L., Escherichia coli, diarrhea